18-Methoxycoronaridine (18-MC) and ibogaine: comparison of antiaddictive efficacy, toxicity, and mechanisms of action. 18-Methoxycoronaridine (18-MC) and ibogaine: comparison of antiaddictive efficacy, toxicity, and mechanisms of action. 18-MC, a novel iboga alkaloid congener, is being developed as a potential treatment for multiple forms of drug abuse. Like ibogaine (40 mg/kg), 18-MC…
Ibogaine: A Novel Anti-Addictive Compound A Comprehensive Literature Review By: Jonathan Freedlander Advisor: Carlo DiClemente, Ph.D. University of Maryland, Baltimore County Introduction and History Ibogaine is a naturally occurring indole alkaloid, found in a variety of African shrubs of the Tabernanthe genus (Obach, Pablo, and Mash, 1998). The root of…
Ibogaine: The Whole Entire Everything (in its complete totality… partially) Copyright © 2005-2008, Patrick K. Kroupa All Rights Reserved “Everything is Poison. Nothing is Poison.” –Paracelsus “I saw the best minds of my generation destroyed by madness, starving hysterical naked, dragging themselves through the negro streets at dawn looking for…
Copyright © 1995, Paul De Rienzo, Dana Beal and Members of the Project All Rights Reserved CHAPTER 18: Deborah Mash’s Brain In March, 1994, in strictest secrecy, Howard Lotsof re-instituted treatments of addict volunteers in an ultramodern hospital in Panama City, with pre-treatment work-ups at the University of Miami. But…
Copyright © 1995-1996, Paul De Rienzo, Dana Beal and Members of the Project All Rights Reserved CHAPTER 13: Bwiti The first time he could sit down with Dhoruba after he came back from Ghana, Dana told him that before, he hadn’t wanted to tell him what to do–but that coming…
Copyright © 1995-1996, Paul De Rienzo, Dana Beal and Members of the Project All Rights Reserved CHAPTER 5: The Staten Island Project In 1981 the marijuana movement was divided between NORML (“the suits”) and a larger group of activists who did smoke-ins. Today’s Drug Reform Movement (the Drug Policy Foundation…