Ibogaine: A Novel Anti-Addictive Compound A Comprehensive Literature Review By: Jonathan Freedlander Advisor: Carlo DiClemente, Ph.D. University of Maryland, Baltimore County Introduction and History Ibogaine is a naturally occurring indole alkaloid, found in a variety of African shrubs of the Tabernanthe genus (Obach, Pablo, and Mash, 1998). The root of…
Original Reference: Nat Prod Lett 2002 Feb;16(1):71-6 Jenks CW. Extraction studies of Tabernanthe iboga and Voacanga africana Abstract: The root bark of Tabernanthe iboga contains ibogaine as its predominant alkaloid and has been an important source of it. Ibogaine is used experimentally to interrupt drug addiction and allow therapeutic intervention,…
Copyright © 1995, Paul De Rienzo, Dana Beal and Members of the Project All Rights Reserved CHAPTER 18: Deborah Mash’s Brain In March, 1994, in strictest secrecy, Howard Lotsof re-instituted treatments of addict volunteers in an ultramodern hospital in Panama City, with pre-treatment work-ups at the University of Miami. But…